Eating just one locally caught freshwater fish could be equivalent to drinking water that’s highly contaminated with “forever chemicals”—or per- and poly-fluoroalkyl substances (PFAS)—for a month, a recent study has found.
Scientists from the Environmental Working Group (EWG), a U.S.-based research and advocacy nonprofit, analyzed U.S. government data derived from 501 samples of fish fillets collected across the United States from 2013 to 2015 under two monitoring programs of the United States Environmental Protection Agency (EPA).
The study found the median level of PFAS in freshwater fish were an astounding 278 times higher than the levels the U.S. Food and Drug Administration detected in commercially-sold fish in 2019–2022.
‘Environmental Injustice’
Authors also reported that perfluorooctanesulfonic acid (PFOS)—a type of PFAS—was the “largest contributor to total PFAS levels” in the freshwater fish, averaging 74 percent of the total.The EPA says that animal lab and human epidemiology studies suggest that exposure to PFOA and/or PFOS “may lead to cancer, reproductive, developmental, cardiovascular, liver, and immunological effects.”
Eating one 8-ounce serving of freshwater fish, assuming median levels of PFOS (8410 ng/kg), would be equivalent to drinking water highly contaminated over one month with PFOS at 48 parts per trillion. That’s a level 2400 greater than the U.S. EPA interim drinking water health advisory.
“These test results are breathtaking,” Scott Faber, EWG’s senior vice president for government affairs, said in a statement. “Eating one bass is equivalent to drinking PFOS-tainted water for a month.”
Authors said their analysis “suggests that a single serving of freshwater fish per year ... translates into a significant increase of PFOS levels in blood serum.”
The EWG says that PFAS contamination threatens those who can’t afford to purchase commercial seafood, and as such, communities that depend on fishing are “inordinately harmed.”
“The exposure to chemical pollutants in freshwater fish across the United States is a case of environmental injustice that especially affects communities that depend on fishing for sustenance and for traditional cultural practices,” authors wrote in the their paper. “Identifying and reducing sources of PFAS exposure is an urgent public health priority.”

Higher PFAS in Great Lakes
The two programs that researchers drew data from were the 2013-2014 National Rivers and Streams Assessment and the 2015 Great Lakes Human Health Fish Fillet Tissue Study.“Of the 349 samples analyzed in the 2013–2014 National Rivers and Streams Assessment, just one sample contained no detectable PFAS,” researchers reported. Meanwhile, “all 152 fish samples tested within the 2015 Great Lakes Human Health Fish Fillet Tissue Study had detectable PFAS.”
Higher levels of PFAS were reported in fish samples from the Great Lakes compared to other rivers and streams across the United States.
“The median level of total targeted PFAS in fish fillets from rivers and streams across the United States was 9,500 ng/kg, with a median level of 11,800 ng/kg in the Great Lakes,” authors wrote.
‘Forever Chemicals’
PFAS were first developed in the 1940s and are used in a wide range of products to resist water and heat, including food packaging, non-stick pans, stain- and water-resistant fabrics and carpets, as well as cleaning products, paints, and fire suppression foams.A number of PFAS chemicals “have been a concern because they do not break down in the environment, can move through soils and contaminate drinking water sources,” according to the Centers for Disease Control (CDC). Because of this, PFAS chemicals are often commonly referred to as “forever chemicals.”