U.S. citizens spend around half their lives ingesting prescription drugs, with the number of people taking five or more drugs at the same time rising, according to recent research.
A 25-year-old man in 2019 would spend 59.4 percent of his remaining life taking prescription medication. For 25-year-old women, this figure was at 71.1 percent.
“It’s important to recognize the central role that prescription drug use has taken on in our lives,” she said. “As an American, I’d like to know what medications I’m putting in my body and how long I can expect to take them.”
The research also sheds light on the issue of polypharmacy—when an individual takes five or more drugs at the same time. Polypharmacy “is high and increasing among adults and children,” with older adults having “the highest levels of polypharmacy,” the study noted.
Among adults aged 65 and above, 42 percent were taking five or more prescription drugs back in 2012, it pointed out. In the current analysis, the study found that a newborn boy born in 2019 would spend 15 percent of his life taking five or more drugs. For a newborn girl, it was 20 percent.
Among 85-year-old men and women in 2019, more than half were estimated to be taking five or more drugs for the remaining part of their lives.
Contributing factors of polypharmacy include “high burdens of chronic disease and multimorbidity, the intensification of treatment for chronic diseases, a growing propensity to treat earlier disease stages (e.g., prediabetes), fragmentation in the health care system, and increasing use of drugs to counter side effects of other drugs.”
Increases in polypharmacy are “particularly impactful for older adults, who are at the greatest risk of experiencing negative effects” due to factors like metabolic changes associated with aging and a higher prevalence of impaired cognition.
The study noted that polypharmacy raises the risks of falls, cognitive impairment, hospitalization, lower quality of life, and mortality.
Gender and Racial Differences
The study found that a majority of women older than 15 take prescription drugs. Among men, this was 40 years. Ms. Ho attributes the trend of women taking prescription drugs at an earlier age in part to birth control and hormonal contraceptives.
“The remaining two-thirds is primarily driven by the use of other hormone-related drugs, painkillers and psychotherapeutic drugs used to treat conditions such as depression, anxiety and ADHD.”
Over-Prescription of Drugs
An over-prescription of drugs can end up causing harm. For instance, amid high antibiotic usage, public health officials have warned that the growth of antibiotic-resistant bacteria is speeding up.Every year, five antibiotic prescriptions are written for every six people in the United States, with a third of them not needed at all.
According to data from the U.S. Centers for Disease Control and Prevention (CDC), over 2.8 million antibiotic-resistant infections occur in the country every year, out of which around 35,000 infections lead to death.
“Per enrollee, use of prescription drugs has also increased in Medicare Part D and Medicaid—from an average of 48 prescriptions per year in 2009 to 54 in 2018 in Medicare Part D, and from 7 prescriptions per year to 11 in Medicaid over that period,” it said.
The report attributed the increased use of prescription drugs primarily to “increasing availability and use of generic drugs, along with the continued development of new treatments.”