Boost Your Brainpower: Try These 4 Essential Nutrients for Cognitive Function

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By Jingduan Yang, M.D.
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Brain health is crucial to our overall well-being, with memory serving as a key indicator of cognitive function. The hippocampus, which plays a central role in learning and memory, naturally deteriorates with age.

This article introduces four essential nutrients that can help protect the hippocampus and improve cognitive function.

Functions of the Hippocampus

Humans have two hippocampi, located in the left and right hemispheres of the brain. The hippocampus has several key functions, including:
  • Processing and storing new information: The hippocampus helps the brain encode and store new information as memories, making it essential for learning.
  • Consolidating and forming memories: The hippocampus consolidates fragmented memories into the brain’s memory system. It is crucial in converting short-term memories into long-term ones, thereby solidifying memory content.
  • Processing spatial memory: The hippocampus is essential for remembering our surroundings and creating cognitive maps.
  • Processing episodic memory: The hippocampus processes and stores episodic memories, which include our daily personal experiences with specific details about time, place, and events.

Effect of Hippocampal Damage on Memory

Damage to the hippocampus leads to short-term memory impairment, affecting the brain’s ability to learn and retain new information. Many people first notice a decline in memory when they begin experiencing difficulties with recent memories.
Additionally, hippocampal damage can result in memory loss, either partial or complete, such as forgetting personal experiences from the past. It can also weaken spatial navigation skills and the ability to remember familiar environments.

Nutrients That Protect the Hippocampus

The hippocampus plays a vital role in memory function and spatial navigation. Clinical evidence suggests that these nutrients and compounds can help protect the hippocampus and enhance memory and cognitive abilities:

Omega-3 fatty acids

Studies have shown that consuming omega-3 fatty acids through diet and supplements can help maintain cognitive function and prevent Alzheimer’s disease.

For example, a woman in her 70s experienced mild cognitive impairment and was treated with high doses of DHA and EPA (two types of omega-3 fatty acids) fish oil supplements. After six months, a follow-up neuropsychological test showed significant improvements in her memory and cognitive function. MRI scans showed that the rate of hippocampal atrophy had slowed, suggesting that omega-3 fatty acids have a protective effect on the hippocampus and can improve overall cognitive performance.

Another patient, a 65-year-old in the early stages of Alzheimer’s disease, took omega-3 supplements for 12 months. During this period, cognitive assessments showed that although his memory function did not reverse, it had stabilized. Brain imaging demonstrated a slower rate of hippocampal atrophy, suggesting that omega-3 fatty acids may have slowed the disease’s progression while supporting hippocampal health.

Antioxidants

Antioxidants, found in various foods and certain supplements, can help protect the hippocampus from oxidative damage.

A 72-year-old man experienced early-stage memory loss. After six months of dietary adjustments, including a higher intake of antioxidant-rich foods such as blueberries and dark chocolate, his cognitive performance improved. His new diet also involved reducing sugar intake and limiting fried foods. As a result, improvements were observed in both his memory and processing speed. Blood tests also showed a reduction in oxidative stress markers.

A randomized controlled trial found that polyphenols in blueberries can improve cognitive function in older adults, improving episodic memory and executive function in those at risk of cognitive decline. Similarly, dark chocolate has been shown to have positive effects on cognitive function.
Another example involves a 65-year-old female patient who experienced memory decline following menopause. She was advised by her doctor to take vitamin C and E supplements. After nine months of treatment, her memory showed significant improvement, particularly in short-term memory. This suggests that the antioxidants vitamins C and E have a protective effect on the hippocampus. Research has shown that supplementing with vitamin C may be a viable strategy for preventing and treating Alzheimer’s disease.

Vitamin B12

Research has established a link between vitamin B12 deficiency and cognitive impairment and hippocampal atrophy. Clinical tests have suggested that supplementing with vitamin B12 can improve cognitive function in patients with B12 deficiency, at least in the short term.
For example, a relatively young female suffered from cognitive decline and memory loss because of a vitamin B12 deficiency. After several months of vitamin B12 injections, her cognition and memory improved significantly. This highlights the importance of considering vitamin B12 deficiency in younger adults experiencing similar issues.

Curcumin

Curcumin has anti-inflammatory and neuroprotective properties that benefit the hippocampus. A comparative study found that curcumin supplementation can significantly delay the progression of Alzheimer’s disease and improve both locomotion and cognitive functions associated with dementia.

In one case, a 60-year-old patient with mild cognitive impairment took a high dose of curcumin alongside other treatments for six months. By the end of the treatment, both his memory and cognitive function had improved, with neuropsychological assessments indicating a partial recovery of his hippocampal function.

Given the individual differences and specific circumstances associated with cognitive health, it is recommended to consult a medical professional for a personalized treatment plan.

Views expressed in this article are the opinions of the author and do not necessarily reflect the views of The Epoch Times. Epoch Health welcomes professional discussion and friendly debate. To submit an opinion piece, please follow these guidelines and submit through our form here.
Jingduan Yang
Jingduan Yang
M.D.
Dr. Jingduan Yang, FAPA, is a board-certified psychiatrist specializing in integrative and traditional Chinese medicine for chronic mental, behavioral, and physical illnesses. Dr. Yang is also the founder and medical director of the Yang Institute of Integrative Medicine and the American Institute of Clinical Acupuncture and the CEO of Northern Medical Center in New York state. He contributed to the books "Integrative Psychiatry," "Medicine Matters," and "Integrative Therapies for Cancer." He also co-authored "Facing East: Ancient Secrets for Beauty+Health for Modern Age" by HarperCollins and "Clinical Acupuncture and Ancient Chinese Medicine" by Oxford Press.
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