Lion’s Mane Mushroom Can Boost Nerve Cell Growth, Enhance Memory: New Study

Lion's Mane mushroom on oak tree in the autumn forest. shutterstock
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Lion’s mane mushroom (Hericium erinaceus) is an edible, medicinal mushroom that can boost nerve cell growth and magnify memory, a recent study suggests.

Lion’s mane mushroom, also known as bearded tooth fungus or monkey’s mane mushroom, is mainly found in the northern temperate zones of Western Europe, North America, Japan, Russia, and China.

By observing the neurotrophic effects of the mushroom extract on rat brain cells, the study by Australian and South Korean universities found that its active compounds can help promote neuronal projections, which allow neurons to extend and connect to other neurons.

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The active compounds had a “significant impact on the growth of brain cells and improving memory,” according to an article by professor Frederic Meunier of the Queensland Brain Institute, who led the experiments with the aid of super-resolution microscopy.

“Extracts from these so-called ‘lion’s mane’ mushrooms have been used in traditional medicine in Asian countries for centuries, but we wanted to scientifically determine their potential effect on brain cells,” Meunier said.

Stewed chicken soup with Hericium erinaceus. Chinese cuisine. (Shutterstock)
Stewed chicken soup with Hericium erinaceus. Chinese cuisine. Shutterstock

In Chinese medicine, the lion’s mane mushroom is widely used as an herbal remedy for indigestion, neurasthenia, and weakness; it’s a delicious and nutritious food.

Dr. Martinez-Marmo, a research fellow at the Queensland Brain Institute and co-author of the paper, said the findings have significance for the treatment and prevention of degenerative cognitive diseases such as Alzheimer’s.

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“Our idea was to identify bioactive compounds from natural sources that could reach the brain and regulate the growth of neurons, resulting in improved memory formation,” he said.

The research was published in January, in the Journal of Neurochemistry.

Research surrounding the effects of lion’s mane mushrooms on the brain has been making progress for the past several years.

A 2013 study in the International Journal of Medicinal Mushrooms found that two compounds contained in the lion’s mane mushroom can stimulate brain cell growth in the laboratory.
In a clinical study published in 2020 in Frontiers in Aging Neuroscience, patients with mild Alzheimer’s disease, after 49 weeks of taking three 350 mg capsules of lion’s mane mushroom daily, showed significant decrease in cognitive decline compared with those who took only a placebo.
The medical mushroom has also been found to be effective in immune enhancement. A 2018 study published in the Journal of Medicinal Food showed that it has anti-anxiety and anti-depressant effects. Another study in BMC Complementary Medicine and Therapies in 2013 proved that Hericium erinaceus has hypoglycemic, hypolipidemic, and antioxidant properties.
Lisa Bian, B.Med.Sc., is a healthcare professional holding a Bachelor's Degree in Medical Science. With a rich background, she has accrued over three years of hands-on experience as a Traditional Chinese Medicine physician. In addition to her clinical expertise, she serves as an accomplished writer based in Korea, providing valuable contributions to The Epoch Times. Her insightful pieces cover a range of topics, including integrative medicine, Korean society, culture, and international relations.
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